Chief of Staff to CEO

Company: Nucleo (YC F25)

Location: San Francisco, CA

Salary: $60k - $120k per year

Posted: 2026-02-01

About this role

This is an early, high-impact role. You’ll work directly with the CEO and help build the company from the inside.


Job Overview
What you’ll do:

  • Partner closely (on a daily basis) with the CEO on all aspects of running the business.
  • Support the CEO in prioritization, communications, and time allocation to ensure focus on the most critical initiatives.
  • Run weekly exec cadences, project trackers, and help prep internal and external communications.
  • Support go-to-market execution: sales ops, outbound campaigns, deal support.
  • Manage and maintain relationships with hospital customers and partners.
  • Support fundraising: investor pipeline, updates, and diligence prep.
  • Keep visibility on company finances: expenses, vendors, basic accounting.
  • Support regulatory execution (FDA / CE): timelines, documentation, coordination

What You’ll Gain

  • Front-row seat to building a YC-backed deep-tech company from zero to scale
  • Daily exposure to high-stakes decisions: hospitals, regulators, investors, and product all at once.
  • The chance to become one of the core operators of the company, not a support role.
  • Ownership that compounds: the more you deliver, the bigger your scope becomes.
  • A trajectory toward senior leadership as we scale.

About You

  • Proven track record of building/scaling a business/project. We don’t care whether your background is business, technical, or something else.
  • You are based in SF or willing to relocate within this year (we can support O-1).
  • You’re willing to work in person and travel when needed.
  • Proven ability to manage multiple priorities in a fast-paced, dynamic environment. Instinct for early-stage scrappiness & hustle.
  • Strong work ethic & execution velocity.

Nice to have
(not required)

  • Experience with hospitals, healthcare procurement, or medical sales.
  • Background in, or passion for, SaaS, AI, or technology companies.
  • Medical training (MD, med student, or formal education in medicine /...

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