Senior Software Engineer II, Cloud Data Pipeline
Company: Nautilus Biotechnology
Location: Seattle, WA
Salary: $164k - $221k per year
Type: Full-time
Posted: 2026-05-01
About this role
At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome -- one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.
We are hiring a
Senior Software Engineer II
to join our Cloud Data Pipeline team. This team is responsible for the data infrastructure that transforms raw protein measurement data into the scientific outputs that our customers and internal researchers depend on. You'll own ETL pipelines, cloud infrastructure, and the APIs and databases that connect our data platform to the rest of the company. As Nautilus moves into commercial deployment, this role sits at the intersection of data engineering rigor and the practical demands of a production scientific platform. Your work will directly shape what our customers can learn from their experiments and how reliably they can trust the results.
This position will report to the Manager, Data Engineering and Cloud Pipelines and is located in Seattle, WA. The position is hybrid and requires a minimum of three days onsite.
Responsibilities
- Design and implement data pipelines and ETLs that process protein measurement data at scale, turning instrument outputs into reliable, query-able scientific results.
- Improve the architecture of existing cloud systems: identify structural weaknesses, propose better approaches, and drive implementation alongside the technical lead.
- Maintain and evolve the APIs and database schemas that serve internal teams including ...