Software Engineer - Python & AWS (we have office locations in Cambridge, Leeds and London)

Responsibilities

Develop and maintain data processing systems within the Scientific R&D team to support genomic sequencing technology assessment. Design and enable research cohorts while writing clean, scalable Python code for cloud and on-premises infrastructure.

Requirements

Requires strong Python skills and hands-on experience with AWS, microservice architectures, and containerised environments. Candidates should have experience working on data-heavy or distributed systems and familiarity with agile delivery.

Skills

• Python
• AWS
• Microservice architectures
• Containerised environments
• Distributed systems
• Big data
• Test-driven development
• Agile
• Terraform
• Spark
• AWS Glue
• Code review
• JavaScript
• Orchestration
• Data processing

Benefits

• 30 days holiday
• Bank holidays
• Remote working abroad
• Blended working arrangements
• Flexible working
• Enhanced maternity leave
• Enhanced paternity leave
• Shared parental leave
• Defined contribution pension
• Life assurance
• Electric vehicle salary sacrifice scheme
• Give as you earn scheme
• Individual learning budgets
• Professional subscription reimbursement
• Employee recognition programme
• Referral scheme
• Subsidised gym membership
• Headspace account
• Employee assistance programme
• Eye tests
• Flu jabs

About this role

Company Description
Genomics England is a global leader in enabling genomic medicine and research, focused on creating a world where everyone benefits from genomic healthcare. Building on the 100,000 Genomes Project, we support the NHS’s world-first national whole genome sequencing service and run the growing National Genomic Research Library, alongside delivering numerous major genomics initiatives. By connecting research and clinical care at national scale, we enable immediate healthcare benefits and advances for the future.
Our mission is to provide the evidence and digital systems so that by 2035 genomics could play a role in up to half of all healthcare interactions, whilst securing the UK’s position as the best place to discover, prove and benefit from genomic innovations.
We are accelerating our impact and working with patients, doctors, scientists, government and industry to improve genomic testing, and help researchers access the health data and technology they need to make new medical discoveries and create more effective, targeted medicines for everybody.
Behind the Healthcare and Research outcomes, Genomics England delivers through designing, developing and operating complex healthcare software systems.
We're on the cusp of big changes with the real prospect of genomics becoming the fabric of everyday healthcare through the lifetime - from birth to old age.
Job Description
Software Engineer - Python & AWS
Genomics England is hiring an experienced Software Engineer with strong Python and AWS experience to join our Scientific R&D team, which sits within our Generate Research Data (GRD) service. GRD works across our organisation and with external partners to generate, obtain and enrich high-quality genomic, multi-omic and clinical datasets.
The service supports the journey from new research studies and emerging technologies through to preparing data for release into the National Genomic Research Library (NGRL), helping enable research, discovery and clinical impact.
The Scientific R&D team develops and tests new genomic and multi-omic approaches and provides scientific expertise across GRD. The team operates wet-lab and bioinformatics capabilities, including long-read sequencing, data analysis, technology assessment and pilot development. It supports programmes such as Cancer 2.0 and Generation Study-related discovery work, while investigating how emerging technologies can be applied to future research.
This Software Engineer role develops and maintains data processing systems within the Scientific R&D team, working across a mixture of cloud and on-premises infrastructure to support the assessment of cutting-edge sequencing technologies for clinical genome sequencing.
What you’ll be doing:
Thinking through, designing and enabling the future facing research cohorts end to end
Writing clean, scalable Python code, following engineering best practices
Developing working solutions to enable processing of long read data, including future facing solutions in AWS
Designing and maintaining services on AWS, with a focus on resilience and performance
Working on distributed systems that handle big data processing at scale
Building and evolving our test automation frameworks
Troubleshooting issues, working closely with colleagues
Staying up to date with the latest tools, libraries and tech approaches
Using GitLab, Jira, and Confluence to work effectively in a modern agile setup
What you’ll bring:
Strong Python skills and experience building scalable backend services
Hands-on experience with AWS, microservice architectures, and containerised environments
Experience working on data-heavy or distributed systems
Familiarity with agile delivery and test-driven development
Self-sufficiency combined with a collaborative mindset and openness to learning from others
Nice to have:
Hands on orchestration skills and experience using Terraform
Experience with big data tools (e.g. Spark, AWS Glue, or similar)
Strong grasp of code review best practices
Some knowledge of JavaScript
Cloud Migration/AWS knowledge
Understanding/experience working with orchestration and data flows
Solution building expertise
Qualifications
BSc in Computer Science or equivalent experience
Additional Information
Closing date for applications: Wednesday 18th November 2026 at 23:00 (UK time)
Salary from: £73,500 per annum
Please note: we are unable to offer visa sponsorship for this role.
Being an integral part of such a meaningful mission is extremely rewarding in itself, but in order to support our people, we’re continually improving our benefits package. We pride ourselves on investing in our people and supporting them to achieve their career goals, as well as offering a benefits package including:
Generous Leave: 30 days’ holiday, plus bank holidays, plus additional leave for long service, and also the option to apply for up to 30 days of remote working abroad annually (approval required).
Family-Friendly: Blended working arrangements, flexible working, enhanced maternity, paternity and shared parental leave benefits.
Pension & Financial: Defined contribution pension (Genomics England double-matches up to 10%, however you can contribute more if you wish), Life Assurance (3x salary), an Electric Vehicle salary sacrifice scheme and a Give As You Earn scheme.
Learning & Development: Individual learning budgets, support for training and certifications, and reimbursement for one annual professional subscription (approval required).
Recognition & Rewards: Employee recognition programme and referral scheme.
Health & Wellbeing: Subsidised gym membership, a free Headspace account, and access to an Employee Assistance Programme, eye tests, flu jabs.
Equal opportunities and our commitment to a diverse and inclusive workplace
Genomics England is actively committed to providing and supporting an inclusive environment that promotes equity, diversity and inclusion best practice both within our community and in ...

About Genomics England

Biotechnology Research · 201-500 employees · headquartered in London · founded 2013