Senior PMO Project Manager - Nemours Children's Hospital, Orlando

About this role

Job Description
Senior Project Manager, Enterprise PMO
Join Nemours Children’s Health
Nemours Children’s Health is seeking a strategic, highly collaborative Senior Project Manager to join our Enterprise Project Management Office. This is an exciting opportunity for an experienced project and program leader who thrives in complex environments, builds alignment across senior stakeholders, and brings structure, momentum, and clarity to initiatives that improve how we deliver care for children and families.


In this role, you will lead high-impact, system-wide projects that may span technology implementations, clinical workflow transformation, business operations, facilities and capital construction, infrastructure upgrades, and multi-vendor delivery models. You will partner with executive leaders and cross-functional teams to move priorities from strategy to execution while supporting Nemours’ mission to help create the healthiest generations of children.


Why This Role Matters
The Senior Project Manager serves as a trusted driver of enterprise change. You will help define scope, manage complex workstreams, anticipate risks, guide decision-making, and ensure initiatives are delivered with discipline, transparency, and measurable impact. Your work will directly support clinical, operational, technical, and facilities teams across a nationally recognized pediatric health system.


What You’ll Do

• Lead large-scale, enterprise-wide initiatives with significant strategic impact.
• Build integrated project and program structures across multiple objectives, dependencies, and workstreams.
• Partner with executive stakeholders to shape project scope, outcomes, governance, and strategic direction.
• Drive alignment across clinical, operational, technical, facilities, finance, and vendor teams.
• Lead organizational change management efforts that support adoption, readiness, and sustainable results.
• Use data, project health indicators, and ri...