Project Manager - EPMO
Company: Avance Clinical Pty Ltd
Location: Sydney, New South Wales (Remote)
Type: Full-time
Remote: Yes
Posted: 2026-09-10
About this role
Avance Clinical is a leading, Australian-headquartered full-service Contract Research Organisation (CRO), supporting pharmaceutical and biotechnology clients from preclinical development through to Phase III clinical trials. Our teams operate across Australia, New Zealand, Asia and North America, bringing together scientific expertise, quality and collaboration to help accelerate the development of new therapies.
We are seeking a capable and delivery-focused Project Manager – EPMO to join our Enterprise Project Management Office. In this role, you will manage internal strategic and operational initiatives that improve how Avance Clinical delivers for its people, clients and business.
Working within our tiered EPMO governance model, you will lead projects aligned to your experience and demonstrated delivery capability—from Tier 1 *Explore* initiatives through to Tier 2 *Build* and Tier 3 *Transform* projects. You will apply sound project-management discipline, partner with senior stakeholders, and help ensure the benefits and return on investment from our internal initiatives are clearly defined, tracked and realised.
What you’ll do
- Lead assigned EPMO projects across Tier 1, Tier 2 and Tier 3 initiatives, applying project-management controls appropriate to the project’s scale, complexity and strategic impact.
- Develop and manage project scope, schedules, budgets, resource plans, risks, issues, changes, stakeholder communications and delivery milestones.
- Work within the EPMO framework, including project intake, prioritisation, governance, reporting, assurance and closeout requirements.
- Partner with business sponsors to develop clear and concise business cases for Tier 2 initiatives, including the rationale, scope, cost, effort, risks, expected outcomes and return on investment.
- Deliver Tier 3 transformation initiatives under the strategic oversight of the EPMO Director, with strong engagement from Executive Leadership Team sponsors.
- C...