Clinical Program Operations Manager, Therapeutics & Innovations

Company: Natera

Location: Location not specified (Remote)

Type: Full-time

Level: Senior

Remote: Yes

Posted: 2026-02-07

About this role

We are seeking a hands-on, execution-focused Clinical Program Operations Manager with deep experience in oncology and clinical trial operations to lead the day-to-day delivery and execution of our therapeutic clinical programs. This role is central to ensuring our studies move forward with precision, on schedule, within scope, and aligned with company goals. You will manage complex timelines, coordinate cross-functional efforts, and support external relationships critical to clinical delivery.


This is a high-impact opportunity for someone who thrives in a fast-moving environment. You’ll bring strong oncology trial experience, a solution-first mindset, and the ability to drive clarity and progress even when priorities shift.


This role is best suited for individuals who thrive in fast-paced, dynamic environments, take initiative, and are comfortable leading through ambiguity. We’re looking for someone sharp, solution-obsessed, and relentless about execution, someone who moves fast, thrives in ambiguity, and gets things done without excuses.


Key Responsibilities


Program Execution & Timeline Management

  • Own, drive, and enforce comprehensive trial timelines, deliverables, and Gantt charts; ensure alignment across functions and hold teams accountable for execution.
  • Identify risks early and fix them fast.
  • Collaborate closely with internal functions (e.g., clinical operations, regulatory, quality, medical) and external CROs/vendors.
  • Ensure real-time visibility of program status for leadership and cross-functional partners.

Operational Leadership

  • Oversee study startup activities, including site selection, feasibility, and trial initiation.
  • Manage CRO relationships and performance, including KPIs, deliverables, and contracts.
  • Ensure operational readiness for investigator meetings, site visits, and data reviews, in collaboration with cross-functional teams.
  • Dive into the weeds when necessary and eliminate roadblocks without...

Create Your Job Alert

Other Clinical Jobs

Other Jobs in Location not specified