Senior Software Engineer & Project Lead, Biology

About this role

**POSITION SUMMARY**

[The Center for Computational Biology](http://www.simonsfoundation.org/flatiron/center-for-computational-biology/) is seeking an experienced software engineer  to be the Project Lead for HumanBase ([hb.flatironinstitute.org](http://hb.flatironinstitute.org)), a dynamic and interactive web-based platform that supports thousands of biomedical researchers in exploring the molecular mechanisms of human disease. This position is ideal for an experienced engineering leader with bioinformatics experience who thrives on solving complex problems at the intersection of large-scale data, advanced analytics, and scientific discovery. This is a high-impact role that directly advances the study of human genomics and disease.

The successful candidate will lead technical direction and execution, guide other software engineers, and collaborate closely with researchers at the Center for Computational Biology to translate cutting-edge computational biology into robust software tools. The Project Lead will be a hands-on engineering leader with experience in biological data and -omics technology, as well as a complementary skillset that includes both writing high-quality code and managing a small team of software engineers. Success in this role depends on the ability to translate biological questions into computational solutions, collaborate closely with internal scientific stakeholders, and drive technically rigorous projects that advance our understanding of human biology.

**ESSENTIAL FUNCTIONS/RESPONSIBILITIES**

• Serve as technical lead for HumanBase, guiding the design, architecture, and implementation of new features and major infrastructure upgrades
• Lead and mentor a team of full stack software engineers, ensuring high-quality code, efficient workflows, and continuous professional development
• Plan, develop, and optimize scalable genomics data processing pipelines
• Integrate machine learning methods into production pipelines to analyze heterog...