Senior Software Engineer, OS Ecosystem

Company: Tempus

Location: Chicago, IL

Salary: $110,000 - $160,000 a year

Type: Full-time

Posted: 2026-05-27

About this role

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

# Summary

Recent advancements in technology have made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

At Tempus, software and AI products are owned and developed by small, autonomous teams composed of engineers, designers, scientists, and product managers. Teams set the goals, build the software, deploy the code, and contribute to a growing suite of capabilities that drives research and delivers advanced diagnostic and treatment improvements for our clinical partners and their patients. Tempus OS is the internal software platform that supports and connects all these teams and their products, enabling them to go farther, faster while safeguarding patient safety and privacy.

# The Role

As a Senior Software Engineer on the OS Ecosystem team, you will act as a core technical contributor in building the foundational infrastructure that powers Tempus’ clinical, research, and AI capabilities. The OS Ecosystem team provides a platform that supports the full lifecycle of data and compute for a multitude of Tempus systems —from the "assembly line" of secure data ingestion, cataloging, and analysis to the orchestration of complex algorithms and models.

You will play a pivotal role in designing and developing systems that allow bioinformatics scientists, ML and Agent developer...

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