Senior Portfolio Operations Program Manager

Company: TRIMEDX

Location: Indianapolis, IN (Remote)

Type: Full-time

Remote: Yes

Posted: 2026-08-17

About this role

If you are wondering what makes Trimedx different, it's that all of our associates share in a common purpose of serving clients, patients, communities, and each other with equal measures of care and performance.

  • Everyone is focused on serving the customer and we do that by collaborating and supporting each other
  • Associates look forward to coming to work each day
  • Every associate matters and makes a difference

It is truly a culture like no other — We hope you will join our team! Find out more about our company and culture here.

The Senior Portfolio Operations Program Manager will lead our portfolio operations and drive speed-to-value across our product and technology teams. This role combines operational excellence with strategic thinking with responsibility to ensure cross-team visibility and coordination while also diagnosing and solving systemic challenges that slow us down. This position will be the connective tissue between product and IT, breaking down silos, removing friction, standardizing ways of working, and helping leadership understand true ROI. As we shift toward speed, agility, and measurable outcomes in an AI-driven landscape, this role will help us adapt quickly and operate at our best.

Responsibilities

  • Portfolio Strategy & Visibility: Own a single source of truth for portfolio health—initiatives, dependencies, blockers, and metrics. Analyze how work flows across product and IT; identify bottlenecks, redundancies, and misalignments. Conduct regular health reviews and escalate risks early, before they derail delivery.
  • Speed-to-Value Framework: Define what "speed" and "value" mean in your context. Build the measurement engine—dashboards, KPIs, and reporting cadences—that tracks cycle time, deployment frequency, time-to-first-value, and ROI. Ensure leadership uses this data for decision-making.
  • Root-Cause Problem-Solving: Lead diagnosis and resolution of high-impact organizational challenges (decision velocity, delivery delays, re...

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